Drew Barrymore, Scream
The opening scene of Scream was iconic thanks to Drew Barrymore’s performance. It turned out Barrymore was really worked up behind the scenes. To capture the needed emotions, Barrymore told director Wes Craven her deepest secrets. Those secrets were used to make her cry before they took a scene.
Source: Endeared
Barrymore wanted to be hyperventilating in every take and Craven had successfully pushed her into a sobbing and shrieking mess for the scene. Barrymore recalled that shooting the scenes was so intense that she was exhausted to the bone each time she went home.